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Such pre-exposure is a standard procedure to guarantee habituation to the exploratory component of the animals behaviour in the open arm, thereby leaving only the aversive component to be evaluated during the first exposure to the mazes open arm 40

Mol Cell Biochem 194:99108 Tsuji N, Moriwaki S, Suzuki Y, Takema Y, Imokawa G (2001) The role of elastases secreted by fibroblasts in wrinkle formation: implication through selective inhibition of elastase activity

Guidelines for implementation of Article 13 of the WHO Framework Convention on Tobacco Control (Tobacco advertising, promotion and sponsorship)