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Following the same search strategy and inclusion criteria as a previous meta-analysis 1,2 , we updated the literature search in 14 databases from the last search date, 1 January to 20 October 2025, and identified an additional 405 studies for eligibility screening
It is 111 years old
Good as a first, anyone, anytime cigar
Hoeper addressing the Sixth International Cancer Congress, Sao Paulo, Brazil It may be concluded that the existing evidence neither proves nor strongly indicates that tobacco smoking and especially cigarette smoking represent a major or even predominating causal factor in the production of cancers in the respiratory tract and are the main reason for the phenomenal increase of pulmonary tumors during recent decades
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