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Half the participants were given access to chewing gum throughout the study, while half were not allowed gum

The cohort consisted of employed men, who would be healthier on average than men from general populations, so the results may underestimate absolute risk, but the relative risks are likely to be generalisable to male populations from similar contexts

and a patient at Jackson Memorial Hospital, Miami, following the introduction of a no-smoking policy at entrances to clinics

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