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The demyelination in the olfactory bulb and tract were mirrored in nearby cortex layers but not deeper in the brain, suggesting to Joseph that perhaps the close proximity of the olfactory bulb/tract and the subjacent cortex provided an important clue, not only about the possible substrate for loss of smell in MS, but also about disease pathogenesis, he wrote in an email

the company convened a standardized management work conference and advanced research on optimizing its innovation system