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But in a randomized trial youre testing a product, treating it like a therapy a medicine to see if an e-cigarette or some other product is more conducive to quitting. In their analysis of observational studies that involved groups of people who already smoked and used e-cigarettes, whether or not they wanted to quit, the team found no appreciable effect of e-cigarettes on participants ability to quit

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Animal models of smoke inhalation injury and related acute and chronic lung diseases

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