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In each city, the sample included quotas for gender (50% male, 50% female), age (50% 1839 years old, 50% 40 years and older) and smoking status (50% cigarette smoker, 50% non-smoker) to ensure that each analysis group had a minimum of 400 participants to achieve statistical power at 0.8 (=0.05) for an effect size of 0.2

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It may also decide to require manufacturers to disclose the contents of their nicotine cartridges