The constraint is that beedis, cigarettes, and RYO differ in how herbal material is presented, which affects packing behavior, airflow characteristics, and end-product uniformity
This may result in a watered-down sample
Now, look at the world from Gods perspective
In that study, conducted among 64 daily e-cigarette users (59 using second- and third-generation devices and 5 using first-generation cigalikes), the levels of chromium and nickel were measured in several samples collected from the e-cigarette device (dispenser, aerosol, and tank) used by the participant, as well as in several biomarkers collected non-invasively: urine, saliva, and exhaled breath condensate (EBC)