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Przulj added, This is the first study to show that refillable e-cigarettes can help people to quit smoking. This was a rigorous and well-conducted trial, which informs an important question: Are e-cigarettes effective for helping smokers quit cigarettes, compared to evidence-based smoking cessation medications? said Rachel Grana, Ph.D., M.P.H., of NCIs Tobacco Control Research Branch (TCRB), who was not involved in the study

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This is typically less than the total nicotine content due to factors like smoke dilution, inhalation depth, and individual metabolism