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According to a 2023 report on nitrous oxide published by the British government, these warning symptoms include: tingling and numbness in the hands or feet, skin crawling, and later, "staggering uncoordinated walk, lower limb weakness, muscles stiffening or tightening, overactive or overresponsive bodily reflexes such as twitching, bladder/bowel complaints of incontinence or retention and sexual dysfunction." The adverse effects of nitrous oxide can be reversed, but only if they are addressed quickly