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NEAT1 was found to be upregulated in COPD patients, and NEAT1 expression could predict decreased COPD susceptibility and acute exacerbation risk, and negatively correlated with GOLD stage and levels of TNF-, IL-1, IL-6 and IL-17 in both Acute Exacerbations of COPD (AECOPD) and stable COPD patients (20,21)
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The population-attributable fractions (PAFs), which estimate the proportion of events that would have been prevented if all individuals had been in the never-smoking category, were calculated [29]
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