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But there are limits to their recommended use: These types of steroids have a risk of serious side effects The course of steroids needs to be carefully tapered off There is potential for rebound worsening of hives For hives lasting a few days, systemic corticosteroids may work quite well, but this is also not a preferred long-term strategy except in very rare cases

The Food and Drug Administration does not require animal testing for product safety -- and there are effective alternatives -- but it's a cheap and easy way for companies to meet their regulatory requirements

H.SeubertS.EllrichmannG.ManzelA.KvakanH.et al (2009)

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