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Key factors contributing to high addiction potential: Rapid Tolerance: Physical dependence can develop within 24 weeks of regular use Severe Withdrawal: Discontinuation can cause seizures, psychosis, and life-threatening complications Protracted Symptoms: Withdrawal can last months or years, complicating recovery Prescription Access: Medical legitimacy masks addiction risk and enables continued use Polysubstance Use: Often combined with opioids, alcohol, or stimulants, increasing overdose risk Benzodiazepines occupy an unusual position on this list