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The higher nicotine content helps replicate the sensation of smoking a traditional cigarette, making the transition smoother and reducing the likelihood of returning to smoking

This means that the industry reaches children and young people in particular

These companies only allow shipping for licensed businesses that have entered into specific, restricted contracts, making them unavailable for individual consumer use

To minimize reverse causality, those who were diagnosed with any cancer (n = 9,069) or cardiovascular disease (stroke [n = 6,186], myocardial infarction [n = 2,828], or HF [n = 1,714]) or who died (n = 665) within 1 year after the second screening date were excluded