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This decrease in hippocampal volume was even greater in individuals with bipolar disorder who used marijuana

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However, another quantitative study by van Mourik et al 43 used a randomised between-subject design (where each subject was exposed to one cigarette and asked to give ratings) to investigate the combination of text warning (Cancer, Heart Disease, Stroke) and drab dark brown cigarette colour and compared it with regular cigarettes and cigarettes that had only a text warning or dark brown colour