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Future research should also address whether CSE-induced downregulation of glycolytic flux is caused by disruption of the transcriptional activity of HIF-1 or by a recently reported mechanism by which HIF-1 is involved in the cytoplasmic formation of a metabolic complex involving several glycolytic enzymes [63]

Deputies located two people who "had been thrown from the boat, were in the water without life jackets" and it was suspected they had "sustained broken bones," the sheriff's office said