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Based on a power calculation using the Clincalc.com (ClinCalc LLC, Arlington Heights, IL, USA) sample size calculator with an assumed average BP of 120 mmHg, a BP variability of 5 mmHg, a clinically relevant difference of 6 mmHg, an enrollment ratio of 3, an alpha of 0.05, and a power of 80%, at least 28 participants, of which at least 7 in each of the cessation and relapse groups, were to be included

Many vaping liquids contain nicotine, which can reduce blood flow to the gums and increase dry mouth, plaque buildup, and gum irritation

This medication should be stored in a cool, dry place, away from direct light and out of reach of children

Be patient and add a little bit at a time