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Altrias shares have fallen by more than 20%over the year, as cigarette smoking continues to decline in the US

The team, led by Prof Robert West at UCL, said: "The increased prevalence of e-cigarettes in England does not appear to have been associated with a detectable change in attempts to stop smoking

While many flavor chemicals in EC are reported safe for use in food 2 , the National Institute for Occupational Safety and Health has warned food-processing workers that some inhaled flavor chemicals may cause lung disease 3 , and the Flavor and Extract Manufacturers Association has strongly cautioned that their Generally Recognized as Safe (GRAS) certification is intended for exposure by ingestion, not inhalation 4