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2023) along with the transient receptor potential (TRP) channels which are a group of ion gated channels mostly located on the plasma membrane of several animal cell types (specifically TRPA1, TRPM8, TRPV1, and TRPV2) (Fernanda et al

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Blood Clot: Since smoking greatly diminishes blood circulation there is a greater chance of clots forming those clots can severely jeopardize your limbs and extremities and lead to amputations