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Relative Cancer Risks from Individual Chemical Components in Cigarette Smoke: Sidestream Smoke (ETS) Cancer Risk Rank (Sidestream) Chemical Relative Risk Scale IARC/USEPA Classification (as of August 1999) 1 1,3 butadiene 100% 2A 2 Acrylonitrile 13.3% 2B 3 NNN 10.7% 2B 3 Benzene 4.2% 1 4 N-nitrosodimethylamine 3.5% 2A 5 Chlorinated dioxins/furans 3.0% 1 6 Acetaldehyde 2.4% 2B 8 Cadmium 1.7% 1 9 Formaldehyde 1.3% 2A 10 Chromium 0.43% 1 N-nitrosodiethylamine 0.22% 2B 11 Benzo(a)pyrene 0.09% 2A NNK 0.04% 2B 7 4-Aminobiphenyl 0.03% 1 12 2-Aminonaphthalene 0.01% 1 13 Nickel 0.004% 1 14 Lead 0.0001% 2B * Calculated using published cancer potency factors (Table 1) combined with quantitative estimates of chemical content in sidestream cigarette smoke (Table 1)