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Interestingly, ustekinumab appears to be the most effective option for treatment of anti-TNF induced psoriasiform skin lesions in IBD, which have been characterized by the presence Th17 and Th1 cell infiltrates and higher concentrations of interleukin (IL)-17A-expressing T cells

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During his 15-year career he was named an All-Star five times, and he won four Gold Glove and two Silver Slugger awards, notably winning both in 2011 and 2014