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Some of the research on the topic shows: Potential for marijuana brain damage and impaired functioning A 2013 systematic review including 43 studies on marijuanas health effects for adults and adolescents found that morphological brain alterations can be found in neuroimaging scans for both adolescent and adult marijuana users

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Am J Health Syst Pharm 77:259268 Bracke KR, Demedts IK, Joos GF, Brusselle GG (2007) CC-chemokine receptors in chronic obstructive pulmonary disease