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Fibroblast-like synoviocytes affected by RA exhibit an induction of proinflammatory cytokinessuch as IL-1a, IL-1B, IL-6, and IL-8, at both mRNA and protein levelsdue to exposure to cigarette smoke condensate 33,34

According to these articles: Tobacco may trigger eczema flare-ups Smoking during pregnancy increases the risk of eczema in the baby If the parents smoke, the risk of eczema in the baby increases Tobacco aggravates eczema on the hands All of the following notions seem well established: Tobacco is an irritant and pollutant that, similarly to pollution, penetrates atopic skin, which tends to have a permeable barrier

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