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This includes drugs that may be beneficial for individuals with cancer, AIDS, multiple sclerosis (MS), and epilepsy

However, there is limited, but consistent evidence from case reports that very high doses of PG administered orally or intravenously to humans can produce toxic effects that appear to be related to osmolar changes in the blood and lactic acid formation secondary to the metabolism of PG

For most smokers, this could appear after 2-3 weeks of using the patches

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