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To think that in 1854, fully 40 years before Robert Koch discovered the bacterium that causes cholera, a lone London obstetrician named John Snow identified the source of a cholera outbreak with pencil, paper, and shoe leather

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The British tobacco giant, which already controls a 42 percent stake in Reynolds, is planning to acquire the remaining 58 percent in a cash-and-stock proposal that values the companys shares at $56.50