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As of July 2025, only thirty-nine ENDS, spanning four manufacturers (Logic, NJOY, Vuse, and Juul), all closed-system ENDS in either tobacco or menthol flavor, have been granted marketing authorization as they were deemed by the FDA Center for Tobacco Products (CTP) to meet the Appropriate for the Protection of Public Health (APPH) standard 6
Butts are counted to document the scope of the problem and then sent off for recycling
Based on life expectancy, education, and income per capita, this category includes medium developed nations such as Vietnam, South Africa, Bangladesh, and Nepal
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