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Their paper, published in the ISME Journal (International Society for Microbial Ecology), found that smoking changes the mouths microbiome, leaving smokers susceptible to tooth decay and oral cancer

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More specifically, IL-6 and IL-33, two pro-inflammatory cytokines produced by airway epithelia known to play key roles in severity of asthma inflammation ( Miro1 deletion in club cells when compared to Ctrl HDM-challenged mice (Figures 3A,B)