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From a research perspective, future studies should prioritize research into gene-environment interactions, such as the regulation of tobacco toxicity by CYP1A1 gene polymorphisms, and the cost-effectiveness of cessation interventions

Among adolescents, the main reasons for experimenting with ECs include curiosity, appealing flavors, consumer friends, and perceived benefits compared to cigarettes 12-14 , due to the belief that ECs are less harmful 14 and help stop smoking 15

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Accessory packs contained powdered coffee, sometimes cocoa powder, salt, pepper, sugar, Chiclets, powdered cream, toilet paper, little P-38 can openers, moisture-proof matches and cigarettes