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The confidence intervals for the results in the present study are comparable with the finding in a much larger prospective study in the UK, which finds that stopping smoking by age 30 avoids about 97% of the increase in risk in continuing smokers 34 and that, although substantial hazard remains for some decades among those who stop at age 40, it is only about one tenth of the excess hazard in those who continue smoking.4 34 Among the smokers in this study, the average number of cigarettes smoked per day increased progressively with decade of birth for cohorts born from the end of the 19th century up until the second world war, while the mean age at starting to smoke decreased progressively (fig 1)