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The half-life of K689R NLRP3 mutant was not changed after CSE exposure, while the wild-type variant had a shortened half-life similar to the endogenous NLRP3 protein (Fig

Scoring and estimation of measures : To facilitate appropriate use of the ABOUT-Dependence measure, a calibrated scoring scheme was developed to enable conversion of unweighted sum scores into linear measures based on weighted likelihood estimation (WLE) 58 , and the calibration was done with the unrestricted Rasch model for polytomous responses 59,60

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