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The Nrf2sMAF heterodimer binds to the antioxidant response element (ARE), which leads to the transcription of genes encoding antioxidant and detoxification enzymes such as SOD, CAT, GP X , heme oxygenase 1 (HO-1), NAD(P)H quinone dehydrogenase 1 (NQO1), which protect cells from oxidative stress and toxins (124126) (Figure 3)
A multivariable logistic regression analysis was also performed with e-cigarette knowledge as the dependent variable and e-cigarette usage, smoking of friends as the independent variable, which showed that the students who have smoking of friends (AOR=1.51
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