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Frequently Asked Questions We have the answers you're looking for Research consistently identifies heroin and other opioids, alcohol, nicotine, cocaine, and methamphetamine as among the most addictive substances based on criteria including compulsive use, tolerance, withdrawal severity, the difficulty of quitting, and the proportion of users who develop dependence

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The needle of the injector was externally rinsed with MeOH for 15 seconds prior to each injection

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