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Researchers from the University of Michigan are showcasing a stark reality faced by individuals with this serious mental illness, which is characterized by extreme mood swings ranging from manic highs to depressive lows

Consistently, in Gpr15 +/+ mice, prolonged cigarette smoke exposure in the TNBS model led to aggravated colitis, as reflected by greater weight loss, elevated DAI, colon shortening, and worsened histological and endoscopic scores, accompanied by increased Gpr15 expression (Supplementary Fig

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Maybe its in the way they look at you after years together, as if theyre seeing you for the first time