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however, they may include delayed gastric emptying that disrupts sleep, rapid blood sugar fluctuations that trigger panic, or the psychological stress of losing food as a primary coping tool
Numerous studies have demonstrated the therapeutic potential of phytomolecules in preclinical cellular and animal PD models, with their ability to exert pleiotropic neuroprotective effects by targeting, inflammatory signaling, mitochondrial dysfunction, S aggregation, and key pathways including sirtuins and PI3K/Akt signaling ( Future research should also aim to disentangle the mechanistic interplay between S accumulation, sirtuin dysregulation, and impaired insulin signaling in PD, to identify which phytomolecules are most effective in counteracting mitochondrial stress, mitophagy defects, and neuronal apoptosis
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Data Availability Statement: All data generated or analyzed during this study are included in this published article
