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These alterations not only extend its duration of action but also enable IGF-1 LR3 to circumvent binding with IGF-binding proteins, which typically impede the biological availability and efficacy of IGF-1

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Thus, aside from ferroptosis, some specific lipid peroxidation products have been demonstrated that contributes to the progression of various types of RCD (e.g., necroptosis, pyroptosis, apoptosis) [9,10,11,12]

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doi: 10.1172/JCI186420

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