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Acne Treatments to Avoid During Pregnancy: Oral isotretinoin and other retinoids (adapalene, tazarotene, tretinoin) Hormone therapies (estrogen, anti-androgens like spironolactone or flutamide) Oral tetracycline antibiotics (doxycycline, minocycline, tetracycline) High-dose salicylic acid treatments These medications can pose serious risks to your baby and should be avoided entirely