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However, one randomized controlled trial studying GLP-1 receptor agonist semaglutide (SUSTAIN-6) indicated the drug was associated with complications of retinopathy, including vitreous hemorrhage and decreased vision in some patients (hazard ratio 1.76)

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Insomnia and Nervous System Suppression Weight-loss drugs often have effects on the nervous system, suppressing appetite

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Using supplements promising weight loss may trigger disordered eating patterns or unhealthy relationships with food and body image

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In conclusion, this first report demonstrated a successful desensitization protocol to exenatide in patients with isolated immediate skin reaction and local reactions and indicated the importance of desensitization in patients who do not have alternative therapies

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