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Freezing can form ice crystals that physically damage the peptide structure

Some people on standard maintenance notice tiredness, brain fog or tingling creeping back well before the next injection is due

10.1109/TBME.2013.2281541 22 GwyerD.WraggN

Extra caution is appropriate in patients with active cancer, recent cancer, unexplained masses, unexplained weight loss, pregnancy, breastfeeding, known allergy to peptide products, active infection, immune compromise, significant liver or kidney disease, active inflammatory or autoimmune disease flares, unusual clotting history, uncontrolled cardiovascular disease, use of chemotherapy or immune-modifying biologic therapy, and competitive athletes subject to anti-doping rules