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Furthermore, clinical manifestations of withdrawal, such as dysphoria and irritability, mirror neurobiological adaptive mechanisms that involve greater stress sensitivity and hyperactivation of the hypothalamic-pituitary-adrenal axis, which could account for the increase in BDNF levels [38, 39]

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Well-diffracting crystals were obtained after a few days in condition G8 of the Pi-PEG screen (Jena Bioscience), containing 34.3% (w/v) PEG 550 monomethyl ether and 2.9% (w/v) PEG 300

27 Homemade diets are increasing in popularity and are a valid diet option when properly formulated to meet the dogs individual nutrient requirements