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doi: 10.1152/ajpendo.2001.281.2.E275 115 SongZ.ChenJ.JiY.YangQ.ChenY.WangF.et al

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Additionally, berberines metabolites, such as berberrubine and palmatine, have been demonstrated to significantly enhance GLP-1 production and glucose-stimulated secretion in GLUTag cells, suggesting a complex metabolic interplay involving both the parent compound and its active derivatives (Weili Yang et al., 2024)