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If you are losing weight steadily at 1.0mg or 1.7mg with manageable side effects, there is no clinical mandate to escalate further

All images were acquired using PALM laser-capture microdissection and an optical tweezer microscope TCS SP8 STED-3 using a magnification of 100 and an ex/em wavelength of 405/468 nm to detect the DAPI signal and 642/690 nm to detect the H2AX signal

What you keep depends on training and nutrition

TNBC cells are highly dependent on exogenous cystine, provided by overexpression of the cystine/glutamate antiporter SLC7A11/xCT, to fuel glutathione synthesis and promote an oxidative stress response consistent with their high metabolic demands