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Furthermore, peripheral insulin resistance triggered by uremia, metabolic acidosis and low-grade inflammation is common in CKD (80), leading to intra-portal hyperinsulinemia, but does not necessarily increase hepatic sensitivity to GH because of the reduced hepatic expression of IGF-I and GHR mRNA (81)
Customized Plan: If Semaglutide or Tirzepatide is recommended, well create a holistic weight loss plan that includes dietary guidance, exercise recommendations, and regular follow-ups for medical monitoring
Biomed Pharmacother 168:115782 Yoon CH et al (2023) 1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface
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