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Many people find success by taking their amlodipine in the morning and their magnesium glycinate in the evening

Stated timing and dose of paracetamol ingestion can be unreliable Check that the laboratory result matches the correct units on the nomogram (in mg/L or micromol/L) Management differs between immediate release, modified release and repeated supratherapeutic paracetamol ingestions Complicated ingestions eg longer-acting forms of paracetamol (modified release, eg Panadol Osteo) or repeated supratherapeutic ingestions should be discussed with Poisons Information Centre or a clinical toxicologist Background Paracetamol is involved in a large proportion of accidental paediatric exposures and deliberate self-poisonings Hepatic failure or death is uncommon in treated individuals Acetylcysteine is a safe and effective antidote