The ensuing negative feedback loop may involve not only EECs but also Paneth cells and intestinal intraepithelial lymphocytes, as these cells have been reported to express the receptor for GLP-1 (namely GLP-1R), and loss of GLP-1R increases the severity of DSS-induced intestinal injury8, 9
The commenter stated that there are implications for group reporting requirements in other programs with respect to data completeness, and whether removing clinicians from the reporting pool would make it mathematically impossible for that group to meet its own program requirements
academic.oup.com/jes/article/9/ GLP-1 in addiction medicine: GLP-1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward/stress hubs (VTA, NAc, ARC, PFC, hypothalamus)
442 Studies have shown that once-daily (2 g1) or twice-daily (1 g2) dosing is associated with 69% or 61% clinical and endoscopic remission rates, respectively