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Therefore, the regulation of Ca 2+ by mitochondria should be an important target for the primary and secondary prevention of a wide range of neurodegenerative diseases (Rodrguez et al., 2022)

Pre-clinical studies have demonstrated that simultaneously activating GLP-1 and inhibiting GIP pathways had a stronger effect on weight loss than targeting either GLP-1 or GIP receptors alone

L-arginine , a semi-essential amino acid, serves as the substrate for nitric oxide synthase (NOS) enzymes, which convert it to nitric oxide and L-citrulline