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When taking higher doses, discontinuation should be done gradually under medical supervision to avoid withdrawal effects, including rebound hypertension

One of the options available to eligible patients is Zepbound , a prescription medication for chronic weight management in adults

If you experience any adverse reactions, you should consult a GP and discontinue use (WebMD)

Tryptophan (Trp) metabolism, and consequently Trp-derived metabolite pathways such as the kynurenine and serotonin pathways, have long been known to be central to the pathophysiology of MDDlower blood concentrations of Trp have been described in several studies of MDD patients, and alterations in tryptophan and kynurenine levels have also been associated with symptomatology and treatment [24, 74]