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meningitidis internalization into HBMEC (Takahashi et al., 2011), and it was proposed that meningococcal internalization into HBMEC might be induced by the reduced environmental glutamate concentration upon infection (Takahashi et al., 2015)

2021;35(4):e21510

Therefore, improving the inflammatory response and oxidative stress in patients with ARDS through metabolic regulation, such as improving mitochondrial function, regulating lipid metabolism, and enhancing the ability of the antioxidant system, may become an important direction for future ARDS treatment strategies