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*Correspondence: Nils Wierup, [email protected] Specialty section: This article was submitted to Neuroendocrine Science, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Bulk-forming laxatives (ispaghula husk, sterculia) and osmotic laxatives (macrogol, lactulose) are first-line treatments, with stimulant laxatives (senna, bisacodyl) reserved for refractory cases

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