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According to the Summary of Product Characteristics (SmPCs), GLP-1 medications commonly cause nausea (reported in approximately 20-40% of patients with semaglutide and 12-21% with dulaglutide), vomiting, and diarrhoea, particularly during initial treatment and dose escalation

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Abbreviations PCOS: Polycystic Ovary Syndrome IR: Insulin Resistance BMI: Body Mass Index LH: Luteinizing Hormone FSH: Follicle-Stimulating Hormone AMH: Anti-Mllerian Hormone GnRH: Gonadotropin-Releasing Hormone HG: Hyperinsulinemia ACTH: Adrenocorticotropic Hormone DHEA: Dehydroepiandrosterone DHEAS: Dehydroepiandrosterone Sulfate HOMA-IR: Homeostatic Model Assessment of Insulin Resistance HDL: High-Density Lipoprotein LDL: Low-Density Lipoprotein VLDL: Very Low-Density Lipoprotein TAC: Total Antioxidant Capacity GSH: Glutathione MDA: Malondialdehyde SHBG: Sex Hormone-Binding Globulin hs-CRP: High-Sensitivity C-Reactive Protein TRPV1: Transient Receptor Potential Vanilloid 1 EPA: Eicosapentaenoic Acid DHA: Docosahexaenoic Acid CoQ10: Coenzyme Q10 NAC: N-Acetyl Cysteine CrP: Chromium Picolinate RCT: Randomized Controlled Trial CC: Clomiphene Citrate LCKD: Low-Carbohydrate Ketogenic Diet GL: Glycemic Load GI: Glycemic Index PP: Premature Pubarche SCAD: Stable Coronary Artery Disease References Raveena, Rani et al