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S2CID 12058906
Methods: PBMC were collected from 15 patients with SLE (7 males, 8 females) and 15 age-matched healthy controls (7 males, 8 females) for proteomic analysis
However, chronic stimulation of these paracrine myofibroblast pathways in IBD raises theoretical safety concerns regarding stricturing, fibrosis risk, and the necessity for rigorous dysplasia surveillance, which remain critical hurdles for long-term clinical development
That number comes from a meta-analysis of 21 semaglutide clinical trials involving over 26,000 participants, and it has understandably alarmed anyone currently injecting this GLP-1 receptor agonist for weight loss or blood sugar management
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