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Allosteric Histidine Switch for Regulation of Intracellular Zinc(II) Fluctuation

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This translates to approximately 16-20 mg total during the loading period, with injections spaced 3-4 days apart for optimal distribution

Conclusion: In patients with anterior LVO and salvageable brain tissue presenting within 4.5 to 24 hours after stroke onset, those with witnessed onset stroke are more likely to achieve better outcomes from tenecteplase compared with wake-up strokes